Development of the crosslinking reactions to RNA triggered by oxidation.
نویسندگان
چکیده
A novel crosslink-forming nucleobase, 2-amino-6-(1-ethylthiovinyl)purine (ATVP), which is triggered by the oxidation of sulfide to sulfoxide, has been developed. The oxidation of ATVP within the duplex proceeded with H2O2 and FeCl2. We have successfully developed the crosslinking reactions activated by oxidation.
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عنوان ژورنال:
- Chemical communications
دوره 50 30 شماره
صفحات -
تاریخ انتشار 2014